Case 1: Progressive vomiting in a three-week-old infant

A 5-Week-Old Boy with a 1-Week History of Vomiting

A 5-week-old male infant presented with a 1-week history of vomiting. His mother stated that the vomiting generally occurred soon after the infant was fed. Initially, the vomiting was infrequent but was progressively worsening. The patient’s mother reported that the infant had been feeding well and had a good appetite. However, he had begun vomiting the entire volume of formula shortly after be...

Nonbilious Vomiting in a 4-Week-Old Male: A Case Report and Review of the Literature

Leukodepletion for acute lymphocytic leukemia in a three-week-old infant.

We report the smallest infant (4.5 kg) to receive leukapheresis as an immediate treatment for Infantile Acute Lymphocytic Leukemia. Leukodepletion helps prevent the risks of hyperviscosity and cerebrovascular and pulmonary leukostasis. In addition, it is a desirable precursor to chemotherapy to potentially reduce metabolic and renal complications associated with rapid cell lysis. Because of thi...

Familial hemophagocytic lymphohistiocytosis in a 6-week-old male infant.

Familial hemophagocytic lymphohistiocytosis (FLH) is an autosomal recessively inherited multisystem disease. This defect in cellular cytotoxicity is a life threatening condition characterized by fever, rash, splenomegaly, cytopenias and neurologic manifestations. PRF1, UNC13D and STX11 gene defects underlie in about 40-50% of primary cases. Chemoimmunotherapy followed by hematopoietic stem cell...

Scalp Swelling in a 10 Week Old Infant

A 10 week old infant presented with a posterior scalp swelling which had increased in size over 1 week. She was otherwise well, thriving and afebrile. She was born at 39+5/40 via ventouse extraction and developed a moderate-sized Subgaleal haemorrhage after delivery. She was observed in the Special Care Nursery for 48hrs and no intervention was required. The Subgaleal haemorrhage had resolved b...